skeleton
• at E16.5, calvarial bone formation and mineralization is reduced compared to in wild-type mice
|
• at E16.5, mice exhibit delayed ossification of the frontal, parietal, and supraoccipital bones compared with wild-type mice
• at E16.5, formation of ossification centers in the proximal phalangeal bones is delayed compared to in wild-type mice
• at E16.5, calvarial bone formation and mineralization is reduced compared to in wild-type mice
• however, embryos appeared normal by E18.5
|
craniofacial
• at E16.5, calvarial bone formation and mineralization is reduced compared to in wild-type mice
|