homeostasis/metabolism
• in mice treated with a high dose of CP 55,940 compared with similarly treated wild-type mice
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• in mice fed a high-fat diet compared with similarly treated wild-type mice
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• when fed a high-fat diet compared with similarly treated wild-type mice
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• when fed a high-fat diet compared with similarly treated wild-type mice
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• in fasted mice
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• in fed and fasted mice
• in mice fed a high-fat diet
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• in fasted mice
• in mice treated with poloxamer 407 (P407) to inhibit lipoprotein lipase activity
• in mice fed a high-fat diet
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• in fasted mice
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• forskolin-stimulated FA and glycerol release from white adipose tissue fat pads are decreased by compared to in wild-type mice
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• modest as indicated by decreased circulating levels of glycerol, ketones, and triglycerides in a fasted state but normal circulating free fatty acid levels
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• mice exhibit an increased tolerance to the hypometabolic activity (decreased locomotor activity and oxygen consumption) induced by a high dose of CP 55,940 compared with wild-type mice
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behavior/neurological
• in mice treated with a high dose of CP 55,940 compared with similarly treated wild-type mice
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• in mice treated with a high dose of CP 55,940 compared with similarly treated wild-type mice
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growth/size/body
N |
• whether fed standard chow or a high fat-diet, mice exhibit normal body weight, fat mass, and lean mass
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liver/biliary system
• in fasted mice
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