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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rr162tm3.1Wtg
targeted mutation 3.1, William T Garrard
MGI:5009316
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rr162tm3.1Wtg/Rr162tm3.1Wtg involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 MGI:5009320


Genotype
MGI:5009320
hm1
Allelic
Composition		 Rr162tm3.1Wtg/Rr162tm3.1Wtg
Genetic
Background		 involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:172855 )
N
• mice exhibit normal B cell development, surface Ig expression, allelic exclusion, Jkappa region usage, Igkappa gene germline levels, and RS recombination
abnormal immunoglobulin V(D)J recombination ( J:172855 )
• mice exhibit skewed Igkappa gene repertoire with decreased distal and enhanced proximal Vkappa gene usage compared with wild-type mice

hematopoietic system
abnormal immunoglobulin V(D)J recombination ( J:172855 )
• mice exhibit skewed Igkappa gene repertoire with decreased distal and enhanced proximal Vkappa gene usage compared with wild-type mice




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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory