All Phenotypes Arhgef7<tm1a(EUCOMM)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Arhgef7^{tm1a(EUCOMM)Wtsi}
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:5009652

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Arhgef7^{tm1a(EUCOMM)Wtsi}/Arhgef7^{tm1a(EUCOMM)Wtsi}	C57BL/6N-Arhgef7^{tm1a(EUCOMM)Wtsi}/Wtsi	MGI:5630861

Allelic Composition	Arhgef7^{tm1a(EUCOMM)Wtsi}/Arhgef7^{tm1a(EUCOMM)Wtsi}
Genetic Background	C57BL/6N-Arhgef7^{tm1a(EUCOMM)Wtsi}/Wtsi
Cell Lines	EPD0766_4_A08

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arhgef7^{tm1a(EUCOMM)Wtsi} mutation (2 available); any Arhgef7 mutation (54 available)

Data Sources

IMPC Data for Arhgef7

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

abnormal placenta morphology ( J:261316 )

• branching morphology defect at E9.5

• fibrotic/acellular lesions at E9.5

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - WTSI

lethality throughout fetal growth and development, complete penetrance ( J:261316 )

• complete lethality at E14.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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