All Phenotypes Adh5<tm1.1Llli> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Adh5^tm1.1Llli
targeted mutation 1.1, Limin Liu
MGI:5049924

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Adh5^tm1.1Llli/Adh5^tm1.1Llli Commd10^{Tg(Vav1-icre)A2Kio}/Commd10⁺	B6.Cg-Adh5^tm1.1Llli Commd10^{Tg(Vav1-icre)A2Kio}	MGI:5049928
cn2	Adh5^tm1.1Llli/Adh5^tm1.1Llli Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺	B6.Cg-Adh5^tm1.1Llli Speer6-ps1^{Tg(Alb-cre)21Mgn}	MGI:5049927

Allelic Composition	Adh5^tm1.1Llli/Adh5^tm1.1Llli Commd10^{Tg(Vav1-icre)A2Kio}/Commd10⁺
Genetic Background	B6.Cg-Adh5^tm1.1Llli Commd10^{Tg(Vav1-icre)A2Kio}

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adh5^tm1.1Llli mutation (0 available); any Adh5 mutation (30 available)
Commd10^{Tg(Vav1-icre)A2Kio} mutation (3 available); any Commd10 mutation (24 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:173666 )

N	• mice exhibit normal survival following diethylnitrosamine (DEN) challenged

Allelic Composition	Adh5^tm1.1Llli/Adh5^tm1.1Llli Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺
Genetic Background	B6.Cg-Adh5^tm1.1Llli Speer6-ps1^{Tg(Alb-cre)21Mgn}

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adh5^tm1.1Llli mutation (0 available); any Adh5 mutation (30 available)
Speer6-ps1^{Tg(Alb-cre)21Mgn} mutation (6 available); any Speer6-ps1 mutation (4 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

increased susceptibility to xenobiotic induced morbidity/mortality ( J:173666 )

• diethylnitrosamine (DEN)-challenged mice exhibit decreased survival compared with similarly treated wild-type mice

increased susceptibility to bacterial infection induced morbidity/mortality ( J:173666 )

• LPS-challenged mice exhibit decreased survival compared with similarly treated wild-type mice

homeostasis/metabolism

increased susceptibility to xenobiotic induced morbidity/mortality ( J:173666 )

• diethylnitrosamine (DEN)-challenged mice exhibit decreased survival compared with similarly treated wild-type mice

immune system

increased susceptibility to bacterial infection induced morbidity/mortality ( J:173666 )

• LPS-challenged mice exhibit decreased survival compared with similarly treated wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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