Phenotypes associated with this allele

• Allele Symbol: Rr14^tm1.1Bulg
• Allele Name: targeted mutation 1.1, Michael Bulger
• Allele ID: MGI:5049943
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rr14^tm1.1Bulg/Rr14^tm1.1Bulg	Not Specified	MGI:5049945

Genotype
MGI:5049945

hm1

• Allelic Composition: Rr14^tm1.1Bulg/Rr14^tm1.1Bulg
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal protein level ( J:173283 )

• normally viable mice show a 20-40% reduction of epsilon y-globin and beta h1-globin mRNAs at E8.5 and at E12.5 in primitive erythroid cells

• no effect on adult beta 1 and beta 2 globins is found in definitive erythroid cells at E14.5