Phenotypes associated with this allele

• Allele Symbol: Lyl1^tm1Mago
• Allele Name: targeted mutation 1, Margaret A Goodell
• Allele ID: MGI:5050110
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lyl1^tm1Mago/Lyl1^tm1Mago	B6.129S7-Lyl1^tm1Mago	MGI:5050112

Genotype
MGI:5050112

hm1

• Allelic Composition: Lyl1^tm1Mago/Lyl1^tm1Mago
• Genetic Background: B6.129S7-Lyl1^tm1Mago

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

hematopoietic system phenotype ( J:173665 )

N • myeloid and lymphoid cell numbers are normal in adults

thrombocytopenia ( J:173665 )

• platelet cell numbers are significantly reduced in adults

abnormal hematopoietic stem cell physiology ( J:173665 )

• stem cells with a limited ability to engraft recipients noticed by 4 weeks

• repopulation is skewed toward myeloid cells