Phenotypes associated with this allele

• Allele Symbol: Tgfb1i1^{tm1a(KOMP)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:5050851
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tgfb1i1^tm1a(KOMP)Wtsi/Tgfb1i1^tm1a(KOMP)Wtsi	involves: C57BL/6N	MGI:5791899

Genotype
MGI:5791899

hm1

• Allelic Composition: Tgfb1i1^{tm1a(KOMP)Wtsi}/Tgfb1i1^{tm1a(KOMP)Wtsi}
• Genetic Background: involves: C57BL/6N
• Cell Lines: EPD0817_1_D04

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

normal phenotype

no abnormal phenotype detected ( J:233538 )

• homozygotes are viable, fertile and healthy with no detectable defects in basic blood and platelet parameters, tail bleeding times, and experimental thrombus formation relative to wild-type controls

• in vitro activation of platelet integrins, degranulation and platelet aggregation are normal under all tested conditions