Phenotypes associated with this allele

• Allele Symbol: Aqp5^{tm1.1(cre)Pfl}
• Allele Name: targeted mutation 1.1, Per Flodby
• Allele ID: MGI:5051940
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Aqp5^tm1.1(cre)Pfl/? Atp1b1^tm1.1Zboro/Atp1b1^tm1.1Zboro	129S-Atp1b1^tm1.1Zboro Aqp5^tm1.1(cre)Pfl	MGI:5788090

Genotype
MGI:5788090

cn1

• Allelic Composition: Aqp5^{tm1.1(cre)Pfl}/?; Atp1b1^tm1.1Zboro/Atp1b1^tm1.1Zboro
• Genetic Background: 129S-Atp1b1^tm1.1Zboro Aqp5^{tm1.1(cre)Pfl}

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

impaired pulmonary alveolar fluid clearance ( J:233742 )

• 43% reduction in alveolar fluid clearance as compared to controls

respiratory system

respiratory system phenotype ( J:233742 )

N • lung permeability, wet-to-dry lung weight rations and lung morphology are similar to controls

impaired pulmonary alveolar fluid clearance ( J:233742 )

• 43% reduction in alveolar fluid clearance as compared to controls