Phenotypes associated with this allele

• Allele Symbol: Tg(Eno2-PSEN2)2348Ykk
• Allele Name: transgene insertion 2348, Yong K Kim
• Allele ID: MGI:5052116
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Eno2-PSEN2)2348Ykk/0	involves: C57BL/6 * DBA/2	MGI:5052119

Genotype
MGI:5052119

tg1

• Allelic Composition: Tg(Eno2-PSEN2)2348Ykk/0
• Genetic Background: involves: C57BL/6 * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal spatial learning ( J:76934 )

• impaired performance in a water maze test at 12 months of age compared to aged matched controls

impaired swimming ( J:76934 )

• slight reduction in swimming speed

nervous system

amyloid beta deposits ( J:76934 )

• increase in amyloid beta 42 levels compared to age matched controls

homeostasis/metabolism

amyloid beta deposits ( J:76934 )

• increase in amyloid beta 42 levels compared to age matched controls

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Alzheimer's disease		DOID:10652		J:76934