Phenotypes associated with this allele

• Allele Symbol: St6galnac2^tm1.1Cfg
• Allele Name: targeted mutation 1.1, Consortium for Functional Glycomics
• Allele ID: MGI:5052157
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	St6galnac2^tm1.1Cfg/St6galnac2^tm1.1Cfg	involves: 129S1/Sv * 129X1/SvJ	MGI:5615585

Genotype
MGI:5615585

hm1

• Allelic Composition: St6galnac2^tm1.1Cfg/St6galnac2^tm1.1Cfg
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

increased B cell proliferation ( J:217719 )

increased pre-B cell number ( J:217719 )

increased spleen germinal center size ( J:217719 )

• prominent germinal centers

decreased IgA level ( J:217719 )

homeostasis/metabolism

decreased circulating creatinine level ( J:217719 )

increased circulating alanine transaminase level ( J:217719 )

growth/size/body

decreased body weight ( J:217719 )

hematopoietic system

increased B cell proliferation ( J:217719 )

abnormal erythropoiesis ( J:217719 )

• elevated Ter-119 and lower frequency of Sca^hi cells

increased pre-B cell number ( J:217719 )

increased spleen germinal center size ( J:217719 )

• prominent germinal centers

decreased IgA level ( J:217719 )

cellular

increased B cell proliferation ( J:217719 )