Phenotypes associated with this allele

• Allele Symbol: Siglech^tm1.1Cfg
• Allele Name: targeted mutation 1, Consortium for Functional Glycomics
• Allele ID: MGI:5052173
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Siglech^tm1.1Cfg/Siglech^tm1.1Cfg	involves: C57BL/6	MGI:5615459

Genotype
MGI:5615459

hm1

• Allelic Composition: Siglech^tm1.1Cfg/Siglech^tm1.1Cfg
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

abnormal seminiferous tubule morphology ( J:217719 )

♂ • with poor maturation

testicular atrophy ( J:217719 )

♂ • with cell degeneration and cystic areas

immune system

immune system phenotype ( J:214874 )

N • plasmacytoid dendritic cells from murine cytomegalovirus (MCMV)-infected mice exhibit normal infection and activation

increased T cell proliferation ( J:217719 )

• after concavalin-A stimulation

renal/urinary system

abnormal renal tubule morphology ( J:217719 )

• vacuolated

homeostasis/metabolism

increased blood urea nitrogen level ( J:217719 )

endocrine/exocrine glands

abnormal seminiferous tubule morphology ( J:217719 )

♂ • with poor maturation

testicular atrophy ( J:217719 )

♂ • with cell degeneration and cystic areas

hematopoietic system

increased T cell proliferation ( J:217719 )

• after concavalin-A stimulation

cellular

increased T cell proliferation ( J:217719 )

• after concavalin-A stimulation