All Phenotypes Ano2<tm1.1Tjj> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ano2^tm1.1Tjj
targeted mutation 1.1, Thomas J Jentsch
MGI:5052299

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ano2^tm1.1Tjj/Ano2^tm1.1Tjj	involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6	MGI:5052302

Allelic Composition	Ano2^tm1.1Tjj/Ano2^tm1.1Tjj
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ano2^tm1.1Tjj mutation (0 available); any Ano2 mutation (57 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

taste/olfaction

• the main olfactory epithelium and vomeronasal organ lack calcium-activated chloride currents unlike wild-type epithelium

• in fluid-phase electro-olfactogram response to an odorant is reduced compared to in wild-type mice

• however, mice exhibit normal air-phase electro-olfactograms and performance in olfactory behavioral tasks

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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