Phenotypes associated with this allele

• Allele Symbol: Dynlrb2^{tm1a(KOMP)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:5052400
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dynlrb2^tm1a(KOMP)Wtsi/Dynlrb2^tm1a(KOMP)Wtsi	C57BL/6N-Dynlrb2^tm1a(KOMP)Wtsi/Wtsi	MGI:5705994
ht2	Dynlrb2^tm1a(KOMP)Wtsi/Dynlrb2^+	C57BL/6N-Dynlrb2^tm1a(KOMP)Wtsi/Wtsi	MGI:5705993

Genotype
MGI:5705994

hm1

• Allelic Composition: Dynlrb2^{tm1a(KOMP)Wtsi}/Dynlrb2^{tm1a(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Dynlrb2^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0823_1_C07

Data Sources

IMPC Data for Dynlrb2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - WTSI

reproductive system

male infertility ( J:211773 )

♂

IMPC - WTSI

Genotype
MGI:5705993

ht2

• Allelic Composition: Dynlrb2^{tm1a(KOMP)Wtsi}/Dynlrb2⁺
• Genetic Background: C57BL/6N-Dynlrb2^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0823_1_C07

Data Sources

IMPC Data for Dynlrb2

adipose tissue

decreased total body fat amount ( J:211773 )

♂

IMPC - WTSI

cardiovascular system

increased heart weight ( J:211773 )

♂

IMPC - WTSI

growth/size/body

increased heart weight ( J:211773 )

♂

IMPC - WTSI

increased lean body mass ( J:211773 )

♂

IMPC - WTSI

hematopoietic system

increased mean platelet volume ( J:211773 )

♂

IMPC - WTSI

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

♀

IMPC - WTSI

increased circulating magnesium level ( J:211773 )

♂

IMPC - WTSI

increased circulating phosphate level ( J:211773 )

♂

IMPC - WTSI