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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Myh6-KDM4A)BZpl
transgene insertion B, Zhi-Ping Liu
MGI:5056132
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(Myh6-KDM4A)BZpl/0 involves: FVB MGI:5056147


Genotype
MGI:5056147
tg1
Allelic
Composition
Tg(Myh6-KDM4A)BZpl/0
Genetic
Background
involves: FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
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phenotype observed in females
phenotype observed in males
N normal phenotype

Tg(Myh6-KDM4A)BZpl/0 mice exhibit cardiac hypertrophy in response to transverse aortic constriction

cardiovascular system
• following transverse aortic constriction
• following transverse aortic constriction
• following transverse aortic constriction, mice exhibit increased left ventricular internal dimension in systole compared with wild-type mice
• following transverse aortic constriction
• following transverse aortic constriction, mice exhibit exacerbated hypertrophic response and loss of cardiac function compared with similarly treated wild-type mice

homeostasis/metabolism
• following transverse aortic constriction, mice exhibit exacerbated hypertrophic response and loss of cardiac function compared with similarly treated wild-type mice

muscle
• following transverse aortic constriction
• following transverse aortic constriction

growth/size/body
• following transverse aortic constriction





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory