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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Scribcrn2
craniorachischisis
MGI:5056373
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Scribcrn2/Scribcrn2 involves: A/J * FVB/N MGI:5056386
cx2
 		Scribcrn2/Scrib+
Vangl2Lp/Vangl2+ 		involves: A/J * FVB/N MGI:5056406


Genotype
MGI:5056386
hm1
Allelic
Composition		 Scribcrn2/Scribcrn2
Genetic
Background		 involves: A/J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scribcrn2 mutation (0 available); any Scrib mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
exencephaly ( J:174027 )
• occasionally

embryo

limbs/digits/tail

hearing/vestibular/ear
abnormal cochlea morphology ( J:174027 )
• shorter but otherwise normal




Genotype
MGI:5056406
cx2
Allelic
Composition		 Scribcrn2/Scrib+
Vangl2Lp/Vangl2+
Genetic
Background		 involves: A/J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scribcrn2 mutation (0 available); any Scrib mutation (54 available)
Vangl2Lp mutation (2 available); any Vangl2 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
craniorachischisis ( J:174027 )
• show either craniorachischisis or loop tail

embryo
craniorachischisis ( J:174027 )
• show either craniorachischisis or loop tail

limbs/digits/tail
curly tail ( J:174027 )
• show either craniorachischisis or loop tail




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory