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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Casp3hith2
hole in the head 2
MGI:5056374
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Casp3hith2/Casp3hith2 involves: A/J * FVB/N MGI:5056387
ht2
 		Casp3hith2/Casp3+ involves: A/J * FVB/N MGI:5056403


Genotype
MGI:5056387
hm1
Allelic
Composition		 Casp3hith2/Casp3hith2
Genetic
Background		 involves: A/J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Casp3hith2 mutation (0 available); any Casp3 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, incomplete penetrance ( J:174027 )
• usually die before birth

nervous system

craniofacial
cleft palate ( J:174027 )
• incompletely penetrant

digestive/alimentary system
cleft palate ( J:174027 )
• incompletely penetrant

growth/size/body
cleft palate ( J:174027 )
• incompletely penetrant




Genotype
MGI:5056403
ht2
Allelic
Composition		 Casp3hith2/Casp3+
Genetic
Background		 involves: A/J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Casp3hith2 mutation (0 available); any Casp3 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory