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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Efnb2tm2.1Henk
targeted mutation 2.1, Mark Henkemeyer
MGI:5085263
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Efnb2tm2.1Henk/Efnb2tm2.1Henk involves: 129 * CD-1 MGI:5085264
ht2
 		Efnb2tm1Henk/Efnb2tm2.1Henk involves: 129 * CD-1 MGI:5085265


Genotype
MGI:5085264
hm1
Allelic
Composition		 Efnb2tm2.1Henk/Efnb2tm2.1Henk
Genetic
Background		 involves: 129 * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Efnb2tm2.1Henk mutation (0 available); any Efnb2 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:173636 )
• many die before adulthood but some can be recovered as adults

digestive/alimentary system
digestive/alimentary phenotype ( J:173636 )
N
• no defects in urorectal, tracheoesophageal or palatal development are seen




Genotype
MGI:5085265
ht2
Allelic
Composition		 Efnb2tm1Henk/Efnb2tm2.1Henk
Genetic
Background		 involves: 129 * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Efnb2tm1Henk mutation (0 available); any Efnb2 mutation (29 available)
Efnb2tm2.1Henk mutation (0 available); any Efnb2 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
hypospadia ( J:173636 )
• seen in 71% of mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory