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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Trp53tm3Att
targeted mutation 3, Laura D Attardi
MGI:5140077
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Trp53tm3Att/Trp53tm3Att involves: 129S4/SvJae MGI:5140102
cn2
 		Trp53tm3Att/Trp53tm3Att
Gt(ROSA)26Sortm1(cre/ERT2)Tyj/? 		involves: 129S4/SvJae MGI:5140103


Genotype
MGI:5140102
cn1
Allelic
Composition		 Trp53tm3Att/Trp53tm3Att
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trp53tm3Att mutation (1 available); any Trp53 mutation (239 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
cellular phenotype ( J:173395 )
N
• cell cycle is arrested by gamma irradiation after treatment with an adenovirus-cre as it is in controls




Genotype
MGI:5140103
cn2
Allelic
Composition		 Trp53tm3Att/Trp53tm3Att
Gt(ROSA)26Sortm1(cre/ERT2)Tyj/?
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(cre/ERT2)Tyj mutation (3 available); any Gt(ROSA)26Sor mutation (992 available)
Trp53tm3Att mutation (1 available); any Trp53 mutation (239 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
cellular phenotype ( J:173395 )
N
• apoptosis observed after tamoxifen treatment and measured 6 hours after gamma irradiation as is observed in controls




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory