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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Crtac1tm1Kota
targeted mutation 1, Kohtaro Takei
MGI:5141316
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Crtac1tm1Kota/Crtac1tm1Kota involves: C57BL/6 MGI:5141317
cx2
 		Crtac1tm1Kota/Crtac1tm1Kota
Rtn4rtm1Stmr/Rtn4rtm1Stmr 		involves: 129X1/SvJ * C57BL/6 MGI:5141318


Genotype
MGI:5141317
hm1
Allelic
Composition		 Crtac1tm1Kota/Crtac1tm1Kota
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crtac1tm1Kota mutation (1 available); any Crtac1 mutation (45 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal axon fasciculation ( J:174418 )
• olfactory bulb axons project caudally in a defasciculated manner, resulting in significantly wider expansion of DiI staining in the lateral olfactory tract
• axonal bundling is decreased in cultured olfactory bulb axons
abnormal olfactory tract morphology ( J:174418 )
• olfactory bulb axons project caudally in a defasciculated manner, resulting in significantly wider expansion of DiI staining in the lateral olfactory tract

cellular
abnormal axon fasciculation ( J:174418 )
• olfactory bulb axons project caudally in a defasciculated manner, resulting in significantly wider expansion of DiI staining in the lateral olfactory tract
• axonal bundling is decreased in cultured olfactory bulb axons




Genotype
MGI:5141318
cx2
Allelic
Composition		 Crtac1tm1Kota/Crtac1tm1Kota
Rtn4rtm1Stmr/Rtn4rtm1Stmr
Genetic
Background		 involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crtac1tm1Kota mutation (1 available); any Crtac1 mutation (45 available)
Rtn4rtm1Stmr mutation (0 available); any Rtn4r mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal olfactory tract morphology ( J:174418 )
• relative width of the lateral olfactory tract is reduced compared to mice homozygous for Crtac1tm1Gosh




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory