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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ascl1tm2Fgu
targeted mutation 2, Francois Guillemot
MGI:5141455
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Ascl1tm2Fgu/Ascl1tm2Fgu Not Specified MGI:5141467


Genotype
MGI:5141467
cn1
Allelic
Composition		 Ascl1tm2Fgu/Ascl1tm2Fgu
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ascl1tm2Fgu mutation (0 available); any Ascl1 mutation (28 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal neuronal migration ( J:174732 )
• mice electroporated with a cre-expressing vector at E14.5 exhibit reduced radial neuronal migration at E17.5 whereby neurons fail to leave the ventricular/subventricular zone and intermediate zone to enter the cortical plate compared with control mice

cellular
abnormal neuronal migration ( J:174732 )
• mice electroporated with a cre-expressing vector at E14.5 exhibit reduced radial neuronal migration at E17.5 whereby neurons fail to leave the ventricular/subventricular zone and intermediate zone to enter the cortical plate compared with control mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory