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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ccdc88ctm1(KOMP)Mbp
targeted mutation 1, Mouse Biology Program, UC Davis
MGI:5141808
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ccdc88ctm1(KOMP)Mbp/Ccdc88ctm1(KOMP)Mbp C57BL/6N-Ccdc88ctm1(KOMP)Mbp MGI:6460125


Genotype
MGI:6460125
hm1
Allelic
Composition		 Ccdc88ctm1(KOMP)Mbp/Ccdc88ctm1(KOMP)Mbp
Genetic
Background		 C57BL/6N-Ccdc88ctm1(KOMP)Mbp
Cell Lines DEPD00564_1_E06
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccdc88ctm1(KOMP)Mbp mutation (1 available); any Ccdc88c mutation (123 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal brain ependyma morphology ( J:292096 )
• loss of dynein at the cell cortex
abnormal brain ependyma motile cilium location or orientation ( J:292096 )
• lack of coordinated cilia orientation and movement on the left ventricle wall

cellular
abnormal brain ependyma motile cilium location or orientation ( J:292096 )
• lack of coordinated cilia orientation and movement on the left ventricle wall




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory