Phenotypes associated with this allele

• Allele Symbol: Mov10^{Gt(IST13267G7)Tigm}
• Allele Name: gene trap IST13267G7, Texas A&M Institute for Genomic Medicine
• Allele ID: MGI:5161082
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mov10^Gt(IST13267G7)Tigm/Mov10^Gt(IST13267G7)Tigm	involves: C57BL/6N	MGI:6154013
ht2	Mov10^Gt(IST13267G7)Tigm/Mov10^+	involves: C57BL/6N	MGI:6154014

Genotype
MGI:6154013

hm1

• Allelic Composition: Mov10^{Gt(IST13267G7)Tigm}/Mov10^{Gt(IST13267G7)Tigm}
• Genetic Background: involves: C57BL/6N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to organogenesis, complete penetrance ( J:251835 )

• no embryos found at E9.5

Genotype
MGI:6154014

ht2

• Allelic Composition: Mov10^{Gt(IST13267G7)Tigm}/Mov10⁺
• Genetic Background: involves: C57BL/6N

behavior/neurological

behavior/neurological phenotype ( J:251835 )

N • behavior in rotarod, trace fear conditioning, and novel object recognition tests

increased anxiety-related response ( J:251835 )

• spent significantly less time in open arms in elevated plus maze test

increased locomotor activity ( J:251835 )

• significant increase in activity in open field test

nervous system

abnormal dendrite morphology ( J:251835 )

• significantly reduced dendritic branching