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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Juntm6.1(Jund)Wag
targeted mutation 6.1, Erwin F Wagner
MGI:5284971
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Juntm6.1(Jund)Wag/Juntm6.1(Jund)Wag involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:5284980
cx2
Juntm6.1(Jund)Wag/Juntm6.1(Jund)Wag
Jundtm1Mya/Jundtm1Mya
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 MGI:5284981


Genotype
MGI:5284980
hm1
Allelic
Composition
Juntm6.1(Jund)Wag/Juntm6.1(Jund)Wag
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Juntm6.1(Jund)Wag mutation (0 available); any Jun mutation (12 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• newborns die within hours of birth
• 65% of mice die between E12.5 and E13.5

nervous system
• in some mice that die between E12.5 and E13.5
• hindbrain

cellular
• in mouse embryonic fibroblasts
• mouse embryonic fibroblasts produce normal amounts of hydrogen peroxide than wild-type cells
• however, hydrogen peroxide production in fetal liver cells is normal

cardiovascular system

embryo
• in some mice that die between E12.5 and E13.5
• in some mice that die between E12.5 and E13.5

vision/eye

liver/biliary system
N
• mice exhibit normal liver development

growth/size/body
• in some mice that die between E12.5 and E13.5




Genotype
MGI:5284981
cx2
Allelic
Composition
Juntm6.1(Jund)Wag/Juntm6.1(Jund)Wag
Jundtm1Mya/Jundtm1Mya
Genetic
Background
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jundtm1Mya mutation (0 available); any Jund mutation (3 available)
Juntm6.1(Jund)Wag mutation (0 available); any Jun mutation (12 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

cellular
• in mouse embryonic fibroblasts
• in mouse embryonic fibroblasts

embryo

growth/size/body





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory