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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cacng4tm1Ran
targeted mutation 1, Roger A Nicoll
MGI:5285084
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cacng4tm1Ran/Cacng4tm1Ran involves: C57BL/6 MGI:5285085


Genotype
MGI:5285085
hm1
Allelic
Composition		 Cacng4tm1Ran/Cacng4tm1Ran
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cacng4tm1Ran mutation (1 available); any Cacng4 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal miniature excitatory postsynaptic currents ( J:175164 )
• both decay and rise times are faster than in controls
• effect lessens with age
decreased miniature excitatory postsynaptic current amplitude ( J:175164 )
• mEPSC currents in the dorsolateral striatum are reduced in amplitude in young animals




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory