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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hsf1tm1.1Echr
targeted mutation 1.1, Elisabeth S Christians
MGI:5285187
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Hsf1tm1.1Echr/Hsf1tm1.1Echr
Tg(Zp3-cre)93Knw/0 		involves: 129S2/SvPas * C57BL/6J MGI:5285188


Genotype
MGI:5285188
cn1
Allelic
Composition		 Hsf1tm1.1Echr/Hsf1tm1.1Echr
Tg(Zp3-cre)93Knw/0
Genetic
Background		 involves: 129S2/SvPas * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hsf1tm1.1Echr mutation (0 available); any Hsf1 mutation (25 available)
Tg(Zp3-cre)93Knw mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal female meiosis ( J:175085 )
• in oocytes chromosomal length is significantly increased at metaphase I
• significantly blocked in the pro-Mi/MI phase
abnormal meiotic spindle assembly checkpoint ( J:175085 )
• persistent activation of the spindle assembly checkpoint

cellular
abnormal female meiosis ( J:175085 )
• in oocytes chromosomal length is significantly increased at metaphase I
• significantly blocked in the pro-Mi/MI phase
abnormal meiotic spindle assembly checkpoint ( J:175085 )
• persistent activation of the spindle assembly checkpoint




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory