About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hsf1tm1.1Echr
targeted mutation 1.1, Elisabeth S Christians
MGI:5285187
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Hsf1tm1.1Echr/Hsf1tm1.1Echr
Tg(Zp3-cre)93Knw/0 		involves: 129S2/SvPas * C57BL/6J MGI:5285188


Genotype
MGI:5285188
cn1
Allelic
Composition		 Hsf1tm1.1Echr/Hsf1tm1.1Echr
Tg(Zp3-cre)93Knw/0
Genetic
Background		 involves: 129S2/SvPas * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hsf1tm1.1Echr mutation (0 available); any Hsf1 mutation (25 available)
Tg(Zp3-cre)93Knw mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal female meiosis ( J:175085 )
• in oocytes chromosomal length is significantly increased at metaphase I
• significantly blocked in the pro-Mi/MI phase
abnormal meiotic spindle assembly checkpoint ( J:175085 )
• persistent activation of the spindle assembly checkpoint

cellular
abnormal female meiosis ( J:175085 )
• in oocytes chromosomal length is significantly increased at metaphase I
• significantly blocked in the pro-Mi/MI phase
abnormal meiotic spindle assembly checkpoint ( J:175085 )
• persistent activation of the spindle assembly checkpoint




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory