Phenotypes associated with this allele

• Allele Symbol: Nrl^{tm1.1(Thrb)Df}
• Allele Name: targeted mutation 1.1, Douglas Forrest
• Allele ID: MGI:5285194
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nrl^tm1.1(Thrb)Df/Nrl^tm1.1(Thrb)Df	involves: C57BL/6	MGI:5285195

Genotype
MGI:5285195

hm1

• Allelic Composition: Nrl^{tm1.1(Thrb)Df}/Nrl^{tm1.1(Thrb)Df}
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

absent retina rod cells ( J:174592 )

increased retina cone cell number ( J:174592 )

short photoreceptor outer segment ( J:174592 )

abnormal retina outer nuclear layer morphology ( J:174592 )

• rosette distortion

abnormal eye physiology ( J:174592 )

• overexpress S and M opsin but with a normal distribution

abnormal rod electrophysiology ( J:174592 )

• lack scotopic ERG responses

nervous system

absent retina rod cells ( J:174592 )

increased retina cone cell number ( J:174592 )

short photoreceptor outer segment ( J:174592 )