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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Dppa3-cre/Esr1*)3Sait
transgene insertion 3, Mitinori Saitou
MGI:5285344
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Smad4tm2.1Cxd/Smad4tm2.1Cxd
Tg(Dppa3-cre/Esr1*)3Sait/0 		involves: 129S6/SvEvTac * C57BL/6 * DBA MGI:5462061


Genotype
MGI:5462061
cn1
Allelic
Composition		 Smad4tm2.1Cxd/Smad4tm2.1Cxd
Tg(Dppa3-cre/Esr1*)3Sait/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * DBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smad4tm2.1Cxd mutation (2 available); any Smad4 mutation (48 available)
Tg(Dppa3-cre/Esr1*)3Sait mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal male meiosis ( J:191052 )
• following tamoxifen treatment at E10.5-E11.5, some male germ cells abnormally enter meiosis at E14.5

cellular
abnormal male meiosis ( J:191052 )
• following tamoxifen treatment at E10.5-E11.5, some male germ cells abnormally enter meiosis at E14.5




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory