Phenotypes associated with this allele

• Allele Symbol: Tet2^tm1.2Rao
• Allele Name: targeted mutation 1.2, Anjana Rao
• Allele ID: MGI:5285413
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tet2^tm1.2Rao/Tet2^tm1.2Rao	involves: C57BL/6NTac	MGI:5285415

Genotype
MGI:5285415

hm1

• Allelic Composition: Tet2^tm1.2Rao/Tet2^tm1.2Rao
• Genetic Background: involves: C57BL/6NTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

abnormal definitive hematopoiesis ( J:175222 )

• extent of hematopoietic reconstitution is increased in a repopulation assay

abnormal myelopoiesis ( J:175222 )

• slight increase in the frequency of myeloid progenitors in the bone marrow

• absolute numbers of LK cells are increased

increased bone marrow cell number ( J:175222 )

• increase in total cell numbers at 8-12 weeks of age

increased hematopoietic stem cell number ( J:175222 )

• significantly greater frequency of HSCs in the bone marrow

• absolute numbers of LSK cells are increased

increased splenocyte number ( J:175222 )

• increase in total cell numbers at 8-12 weeks of age

immune system

abnormal myelopoiesis ( J:175222 )

• slight increase in the frequency of myeloid progenitors in the bone marrow

• absolute numbers of LK cells are increased

increased splenocyte number ( J:175222 )

• increase in total cell numbers at 8-12 weeks of age