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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mettm1Ics
targeted mutation 1, Mouse Clinical Institute
MGI:5285647
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Mettm1Ics/Mettm1Sst
Tg(Nes-cre)1Kln/0 		involves: 129P2/OlaHsd * C57BL/6 * SJL MGI:5285658


Genotype
MGI:5285658
cn1
Allelic
Composition		 Mettm1Ics/Mettm1Sst
Tg(Nes-cre)1Kln/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mettm1Ics mutation (0 available); any Met mutation (83 available)
Mettm1Sst mutation (1 available); any Met mutation (83 available)
Tg(Nes-cre)1Kln mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased motor neuron number ( J:174591 )
• by P2 with no further reduction in adult mice
• lacZ+ motor neurons are reduced at P2 in C8 and T1 regions of the spinal cord




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory