All Phenotypes Tgfbr1<R244Q> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tgfbr1^R244Q
Arg244Gln
MGI:5285662

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tgfbr1^R244Q/Tgfbr1^R244Q	either: (involves: C57BL/6) or (involves: BALB/c * C57BL/6)	MGI:5285667
ht2	Tgfbr1^R244Q/Tgfbr1⁺	either: (involves: C57BL/6) or (involves: BALB/c * C57BL/6)	MGI:5285668

Allelic Composition	Tgfbr1^R244Q/Tgfbr1^R244Q
Genetic Background	either: (involves: C57BL/6) or (involves: BALB/c * C57BL/6)

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tgfbr1^R244Q mutation (0 available); any Tgfbr1 mutation (36 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

enhanced wound healing ( J:175236 )

• fast and regenerative wound healing in an ear hole punch test

• phenotype is more pronounced in homozygotes compared to heterozygotes

skeleton

abnormal cartilage development ( J:175236 )

• bone marrow-derived mesenchymal stromal cells display accelerated chondrogenesis

Allelic Composition	Tgfbr1^R244Q/Tgfbr1⁺
Genetic Background	either: (involves: C57BL/6) or (involves: BALB/c * C57BL/6)