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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hoxa1tm8.2Mrc
targeted mutation 8.2, Mario R Capecchi
MGI:5287662
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Hoxa1tm8.2Mrc/Hoxa1tm8.2Mrc involves: 129S1/Sv * C57BL/6 * SJL MGI:5287663


Genotype
MGI:5287663
hm1
Allelic
Composition		 Hoxa1tm8.2Mrc/Hoxa1tm8.2Mrc
Genetic
Background		 involves: 129S1/Sv * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxa1tm8.2Mrc mutation (0 available); any Hoxa1 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
neonatal lethality, complete penetrance ( J:175781 )
• die shortly after birth

hearing/vestibular/ear
abnormal otic vesicle development ( J:175781 )
• the vesicle forms but fails to differentiate




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory