Phenotypes associated with this allele

• Allele Symbol: Ly86^{tm1a(KOMP)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:5287791
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ly86^tm1a(KOMP)Wtsi/Ly86^tm1a(KOMP)Wtsi	C57BL/6N-Ly86^tm1a(KOMP)Wtsi/MbpMmucd	MGI:6492942
ht2	Ly86^tm1a(KOMP)Wtsi/Ly86^+	C57BL/6N-Ly86^tm1a(KOMP)Wtsi/MbpMmucd	MGI:7551159

Genotype
MGI:6492942

hm1

• Allelic Composition: Ly86^{tm1a(KOMP)Wtsi}/Ly86^{tm1a(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Ly86^{tm1a(KOMP)Wtsi}/MbpMmucd
• Cell Lines: EPD0855_4_C01

Data Sources

IMPC Data for Ly86

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

♀

IMPC - UCD

cardiovascular system

increased heart weight ( J:211773 )

♀

IMPC - UCD

growth/size/body

increased heart weight ( J:211773 )

♀

IMPC - UCD

increased lean body mass ( J:211773 )

♀

IMPC - UCD

hematopoietic system

increased leukocyte cell number ( J:211773 )

♀

IMPC - UCD

increased lymphocyte cell number ( J:211773 )

♀

IMPC - UCD

immune system

increased leukocyte cell number ( J:211773 )

♀

IMPC - UCD

increased lymphocyte cell number ( J:211773 )

♀

IMPC - UCD

Genotype
MGI:7551159

ht2

• Allelic Composition: Ly86^{tm1a(KOMP)Wtsi}/Ly86⁺
• Genetic Background: C57BL/6N-Ly86^{tm1a(KOMP)Wtsi}/MbpMmucd
• Cell Lines: EPD0855_4_C01

Data Sources

IMPC Data for Ly86

adipose tissue

decreased total body fat amount ( J:211773 )

♂

IMPC - UCD

hematopoietic system

increased leukocyte cell number ( J:211773 )

♂

IMPC - UCD

increased lymphocyte cell number ( J:211773 )

♂

IMPC - UCD

homeostasis/metabolism

increased circulating aspartate transaminase level ( J:211773 )

♂

IMPC - UCD

immune system

increased leukocyte cell number ( J:211773 )

♂

IMPC - UCD

increased lymphocyte cell number ( J:211773 )

♂

IMPC - UCD