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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lmx1atm1.1Tpe
targeted mutation 1.1, Thomas Perlmann
MGI:5287979
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Lmx1atm1.1Tpe/Lmx1atm1.1Tpe involves: 129S7/SvEvBrd * C57BL/6J MGI:5287981


Genotype
MGI:5287981
hm1
Allelic
Composition		 Lmx1atm1.1Tpe/Lmx1atm1.1Tpe
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lmx1atm1.1Tpe mutation (0 available); any Lmx1a mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased dopaminergic neuron number ( J:175535 )
• expression analysis indicates a decrease in the number of dopaminergic neurons in the ventral midbrain at E11.5 and E13.5




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory