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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dcdc2atm1.2Jjlo
targeted mutation 1.2, Joseph J LoTurco
MGI:5288003
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dcdc2atm1.2Jjlo/Dcdc2atm1.2Jjlo involves: 129S1/Sv * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 MGI:5443916
hm2
 		Dcdc2atm1.2Jjlo/Dcdc2atm1.2Jjlo involves: 129S/Sv * C57BL/6 MGI:5288004


Genotype
MGI:5443916
hm1
Allelic
Composition		 Dcdc2atm1.2Jjlo/Dcdc2atm1.2Jjlo
Genetic
Background		 involves: 129S1/Sv * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dcdc2atm1.2Jjlo mutation (0 available); any Dcdc2a mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
impaired short-term object recognition memory ( J:188826 )
• impaired short-term familiar object recognition
abnormal spatial learning ( J:188826 )
• impaired visuo-spatial learning and memory
abnormal spatial working memory ( J:188826 )
• impaired visuo-spatial learning and memory
increased anxiety-related response ( J:188826 )
• in a Hebb-Williams maze




Genotype
MGI:5288004
hm2
Allelic
Composition		 Dcdc2atm1.2Jjlo/Dcdc2atm1.2Jjlo
Genetic
Background		 involves: 129S/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dcdc2atm1.2Jjlo mutation (0 available); any Dcdc2a mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:175635 )
N
• normal behavior and brain morphology and development

behavior/neurological
behavior/neurological phenotype ( J:175635 )
N
• normal behavior and brain morphology and development




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory