Phenotypes associated with this allele

• Allele Symbol: Nrp1^tm1.1Cruh
• Allele Name: targeted mutation 1.1, Christiana Ruhrberg
• Allele ID: MGI:5288597
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nrp1^tm1.1Cruh/Nrp1^tm1.1Cruh	involves: C57BL/6	MGI:5288598

Genotype
MGI:5288598

hm1

• Allelic Composition: Nrp1^tm1.1Cruh/Nrp1^tm1.1Cruh
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal retina blood vessel pattern ( J:176047 )

• significant increase in artery vein crossing points

• arteries are positioned anteriorly to veins in the crossing points

cardiovascular system

cardiovascular system phenotype ( J:176047 )

N • unlike in null mice, embryonic vasculogenesis and angiogenesis are normal

abnormal retina blood vessel pattern ( J:176047 )

• significant increase in artery vein crossing points

• arteries are positioned anteriorly to veins in the crossing points

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
retinal vein occlusion		DOID:1727		J:176047