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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Actb-GFP,-Bmp4)1Csk
transgene insertion 1, Chugai Pharmaceutical Co, Ltd
MGI:5291512
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Tg(Actb-GFP,-Bmp4)1Csk/0
Tg(CAG-cre/Esr1*)67Csk/0
C57BL/6-Tg(Actb-GFP,-Bmp4)1Csk Tg(CAG-cre/Esr1*)67Csk MGI:5291625


Genotype
MGI:5291625
cn1
Allelic
Composition
Tg(Actb-GFP,-Bmp4)1Csk/0
Tg(CAG-cre/Esr1*)67Csk/0
Genetic
Background
C57BL/6-Tg(Actb-GFP,-Bmp4)1Csk Tg(CAG-cre/Esr1*)67Csk
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• albuminuria is markedly increased in mice following induction; increase correlates with mesangial expansion

renal/urinary system
• albuminuria is markedly increased in mice following induction; increase correlates with mesangial expansion
• expansion of the mesangial matrix and thickening of the glomerular basement membrane (GBM) is observed after tamoxifen induction
• after tamoxifen induction, animals develop glomerulosclerosis





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory