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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(CEPHY230E8)50Hgc
transgene insertion 50, Edward M Rubin
MGI:5291633
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(CEPHY230E8)50Hgc/0 (C57BL/6 x FVB/N)F1 MGI:5320167


Genotype
MGI:5320167
tg1
Allelic
Composition
Tg(CEPHY230E8)50Hgc/0
Genetic
Background
(C57BL/6 x FVB/N)F1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(CEPHY230E8)50Hgc mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• in the reverse platform test of the Morris water maze, mutants show decreases in latency to find the novel position for the invisible platform, however this decrease is less than seen in controls, indicating a learning deficit
• in the reverse probe test, mutants spend the same amount of time as controls in the quadrant of the pool where the reversed platform had been located, however mutants cross the position of the platform much less frequently

nervous system
• mutants exhibit greater cerebral cortical neuronal density than controls





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory