Phenotypes associated with this allele

• Allele Symbol: Pax3^{tm6(Pax8)Buck}
• Allele Name: targeted mutation 6, Margaret E Buckingham
• Allele ID: MGI:5291649
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pax3^tm6(Pax8)Buck/Pax3^tm6(Pax8)Buck	involves: 129S2/SvPas	MGI:5291832
ht2	Pax3^tm6(Pax8)Buck/Pax3^+	involves: 129S2/SvPas	MGI:5291833

Genotype
MGI:5291832

hm1

• Allelic Composition: Pax3^{tm6(Pax8)Buck}/Pax3^{tm6(Pax8)Buck}
• Genetic Background: involves: 129S2/SvPas

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal neural crest cell migration ( J:176192 )

open neural tube ( J:176192 )

nervous system

open neural tube ( J:176192 )

absent dorsal root ganglion ( J:176192 )

muscle

absent skeletal muscle ( J:176192 )

• in the limb

cellular

abnormal neural crest cell migration ( J:176192 )

Genotype
MGI:5291833

ht2

• Allelic Composition: Pax3^{tm6(Pax8)Buck}/Pax3⁺
• Genetic Background: involves: 129S2/SvPas

pigmentation

belly spot ( J:176192 )

• as in mice heterozygous for a null allele

muscle

abnormal muscle development ( J:176192 )

• in the limb

abnormal myotome development ( J:176192 )

integument

belly spot ( J:176192 )

• as in mice heterozygous for a null allele