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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rtn4rl2tm1Yanr
targeted mutation 1, Riqiang Yan
MGI:5292066
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rtn4rl2tm1Yanr/Rtn4rl2tm1Yanr involves: 129S6/SvEvTac * C57BL/6J MGI:5292070
cx2
 		Rtn4rl2tm1Yanr/Rtn4rl2tm1Yanr
Tg(APPswe,PSEN1dE9)85Dbo/0 		involves: 129S6/SvEvTac * C3H * C57BL/6 * C57BL/6J MGI:5292071


Genotype
MGI:5292070
hm1
Allelic
Composition		 Rtn4rl2tm1Yanr/Rtn4rl2tm1Yanr
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rtn4rl2tm1Yanr mutation (0 available); any Rtn4rl2 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:175718 )
• mice exhibit no discernible abnormalities




Genotype
MGI:5292071
cx2
Allelic
Composition		 Rtn4rl2tm1Yanr/Rtn4rl2tm1Yanr
Tg(APPswe,PSEN1dE9)85Dbo/0
Genetic
Background		 involves: 129S6/SvEvTac * C3H * C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rtn4rl2tm1Yanr mutation (0 available); any Rtn4rl2 mutation (24 available)
Tg(APPswe,PSEN1dE9)85Dbo mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
amyloid beta deposits ( J:175718 )
• mice exhibit reduced amyloid plaque production compared to in Tg(APPswe,PSEN1dE9)85Dbo mice

homeostasis/metabolism
amyloid beta deposits ( J:175718 )
• mice exhibit reduced amyloid plaque production compared to in Tg(APPswe,PSEN1dE9)85Dbo mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory