All Phenotypes Tet1<tm1.1Jae> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tet1^tm1.1Jae
targeted mutation 1.1, Rudolf Jaenisch
MGI:5292563

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tet1^tm1.1Jae/Tet1^tm1.1Jae	involves: 129S4/SvJae * C57BL/6	MGI:5292569

Allelic Composition	Tet1^tm1.1Jae/Tet1^tm1.1Jae
Genetic Background	involves: 129S4/SvJae * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tet1^tm1.1Jae mutation (1 available); any Tet1 mutation (142 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

decreased litter size ( J:175858 )

• smaller than average litters

growth/size/body

embryonic growth retardation ( J:175858 )

• mild with variable size/development at E12.5

decreased birth body size ( J:175858 )

• in 13 of 17 mice

decreased body size ( J:175858 )

• at 3 weeks but mice gain weight with age

immune system

decreased neutrophil cell number ( J:175858 )

• slight

embryo

embryonic growth retardation ( J:175858 )

• mild with variable size/development at E12.5

hematopoietic system

decreased neutrophil cell number ( J:175858 )

• slight

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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