All Phenotypes Apba3<tm1.1Ski> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Apba3^tm1.1Ski
targeted mutation 1.1, Motoharu Seiki
MGI:5293146

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Apba3^tm1.1Ski/Apba3^tm1.1Ski Lyz2^tm1(cre)Ifo/Lyz2⁺	B6.129-Apba3^tm1.1Ski Lyz2^tm1(cre)Ifo	MGI:5293148

Allelic Composition	Apba3^tm1.1Ski/Apba3^tm1.1Ski Lyz2^tm1(cre)Ifo/Lyz2⁺
Genetic Background	B6.129-Apba3^tm1.1Ski Lyz2^tm1(cre)Ifo

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apba3^tm1.1Ski mutation (0 available); any Apba3 mutation (22 available)
Lyz2^tm1(cre)Ifo mutation (14 available); any Lyz2 mutation (40 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

decreased susceptibility to xenobiotic induced morbidity/mortality ( J:176742 )

• in LPS-treated mice

immune system

decreased susceptibility to endotoxin shock ( J:176742 )

• LPS-treated mice exhibit increased survival compared with similarly treated wild-type mice

homeostasis/metabolism

decreased susceptibility to xenobiotic induced morbidity/mortality ( J:176742 )

• in LPS-treated mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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