Analysis Tools|
Allele Symbol Allele Name Allele ID |
Slc38a2tm1a(KOMP)Wtsi targeted mutation 1a, Wellcome Trust Sanger Institute MGI:5293947 |
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| Summary |
4 genotypes
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Data Sources
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• die shortly after birth
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Data Sources
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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IMPC - WTSI
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IMPC - WTSI
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IMPC - WTSI
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IMPC - WTSI
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IMPC - WTSI
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IMPC - WTSI
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IMPC - WTSI
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IMPC - WTSI
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• impaired alveolar fluid clearance based on elevated wet to dry lung weight ratio after 30 min of continuous perfusion and mechanical ventilation
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• following elevation of left atrial pressure to induce cardiogenic lung edema wet to dry lung weight ratio is markedly increased compared to only a moderate but non-significant increase in wild-type controls
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• impaired alveolar fluid clearance based on elevated wet to dry lung weight ratio after 30 min of continuous perfusion and mechanical ventilation
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• following elevation of left atrial pressure to induce cardiogenic lung edema wet to dry lung weight ratio is markedly increased compared to only a moderate but non-significant increase in wild-type controls
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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