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Allele Symbol Allele Name Allele ID |
Cd8atm1.1(cre)Koni targeted mutation 1.1, Pandelakis A Koni MGI:5294414 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice have greatly reduced numbers of CD8 T cells, with only 13% of wild-type level of Cd8a expression
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• mice have greatly reduced numbers of CD8 T cells, with only 13% of wild-type level of Cd8a expression
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice are viable, fertile, and normal in size
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| N |
• mice have normal numbers of CD8 T cells in lymphoid organs, despite a 35% reduction of Cd8a expression
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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