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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Psip1tm1Eng
targeted mutation 1, Alan Engelman
MGI:5294949
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Psip1tm1Eng/Psip1tm1Eng involves: 129S6/SvEvTac * C57BL/6 MGI:5294951
cn2
 		Psip1tm1Eng/Psip1tm1Eng
Edil3Tg(Sox2-cre)1Amc/Edil3+ 		involves: 129S6/SvEvTac * C57BL/6 * CBA MGI:5294952


Genotype
MGI:5294951
hm1
Allelic
Composition		 Psip1tm1Eng/Psip1tm1Eng
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Psip1tm1Eng mutation (1 available); any Psip1 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:177408 )
• mice are viable, fertile, normal in size, and do not display any gross physical or behavioral abnormalities




Genotype
MGI:5294952
cn2
Allelic
Composition		 Psip1tm1Eng/Psip1tm1Eng
Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edil3Tg(Sox2-cre)1Amc mutation (5 available); any Edil3 mutation (43 available)
Psip1tm1Eng mutation (1 available); any Psip1 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cell physiology ( J:177408 )
• cells exhibit defective HIV-1 integration compared with wild-type cells




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory