All Phenotypes Fat3<tm1.1Good> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Fat3^tm1.1Good
targeted mutation 1.1, Lisa Goodrich
MGI:5295414

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Fat3^tm1.1Good/Fat3^tm1.2Good Ptf1a^{tm1.1(cre)Cvw}/Ptf1a⁺	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ	MGI:5295430

Allelic Composition	Fat3^tm1.1Good/Fat3^tm1.2Good Ptf1a^{tm1.1(cre)Cvw}/Ptf1a⁺
Genetic Background	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fat3^tm1.1Good mutation (1 available); any Fat3 mutation (241 available)
Fat3^tm1.2Good mutation (0 available); any Fat3 mutation (241 available)
Ptf1a^{tm1.1(cre)Cvw} mutation (1 available); any Ptf1a mutation (31 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

abnormal retina neuronal layer morphology ( J:176668 )

• amacrine cells form an additional plexiform layers (outer misplaced plexiform layers) compared with wild-type mice

• amacrine cells develop bipolar morphologies

• however, amacrine cell migration is normal and no inner misplaced plexiform layer is formed

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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