vision/eye
N |
• retinas exhibit normal planar cell polarity
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• mice exhibit a disruption in the distribution of glycinergic amacrine cells and starburst cells
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• amacrine cells are mislocalized in the ganglion cell layers
• fewer calretinin+ amacrine cells are found in the inner nuclear layer compared to in wild-type mice
• All amacrine cells are mispositioned within the inner nuclear layer
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• rod bipolar cells frequently overshoot the inner plexiform layer and form ectopic endings in the nerve fiber layer
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• amacrine cells form two additional plexiform layers (inner and outer misplaced plexiform layers) compared with wild-type mice
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• due to displaced amacrine cells
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nervous system
• amacrine cells are mislocalized in the ganglion cell layers
• fewer calretinin+ amacrine cells are found in the inner nuclear layer compared to in wild-type mice
• All amacrine cells are mispositioned within the inner nuclear layer
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• rod bipolar cells frequently overshoot the inner plexiform layer and form ectopic endings in the nerve fiber layer
|