All Phenotypes Plk4<m1Lja> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Plk4^m1Lja
mutation 1, J Larry Jameson
MGI:5296670

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Plk4^m1Lja/Plk4^m1Lja	C57BL/6J-Plk4^m1Lja	MGI:5296675
ht2	Plk4^m1Lja/Plk4⁺	C57BL/6J-Plk4^m1Lja	MGI:5296676
ht3	Plk4^Gt(XK603)Byg/Plk4^m1Lja	involves: 129P2/OlaHsd * C57BL/6J	MGI:5296674

Allelic Composition	Plk4^m1Lja/Plk4^m1Lja
Genetic Background	C57BL/6J-Plk4^m1Lja

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plk4^m1Lja mutation (0 available); any Plk4 mutation (38 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:177071 )

Allelic Composition	Plk4^m1Lja/Plk4⁺
Genetic Background	C57BL/6J-Plk4^m1Lja

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plk4^m1Lja mutation (0 available); any Plk4 mutation (38 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reproductive system phenotype ( J:177071 )

N	• male mice exhibit normal fertility

decreased male germ cell number ( J:177071 )

small testis ( J:177071 )

decreased testis weight ( J:177071 )

• at P31 but not P10

homeostasis/metabolism

increased circulating follicle stimulating hormone level ( J:177071 )

• 2-fold

endocrine/exocrine glands

small testis ( J:177071 )

decreased testis weight ( J:177071 )

• at P31 but not P10

cellular

decreased male germ cell number ( J:177071 )

Allelic Composition	Plk4^Gt(XK603)Byg/Plk4^m1Lja
Genetic Background	involves: 129P2/OlaHsd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plk4^Gt(XK603)Byg mutation (0 available); any Plk4 mutation (38 available)
Plk4^m1Lja mutation (0 available); any Plk4 mutation (38 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:177071 )

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