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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
S100a8tm1Hogg
targeted mutation 1, Nancy Hogg
MGI:5296777
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
S100a8tm1Hogg/S100a8tm1Hogg B6.129P2-S100a8tm1Hogg MGI:5296778
hm2
S100a8tm1Hogg/S100a8tm1Hogg involves: 129P2/OlaHsd * C57BL/6J * CD-1 MGI:5296779


Genotype
MGI:5296778
hm1
Allelic
Composition
S100a8tm1Hogg/S100a8tm1Hogg
Genetic
Background
B6.129P2-S100a8tm1Hogg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
S100a8tm1Hogg mutation (0 available); any S100a8 mutation (10 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• fewer than expected embryos are found at E2.5, E3.5, and E4.5 suggesting lethality occurs before the 8 cell stage
• none present at birth
• no embryos survive past implantation
• tetraploid complementation fails to rescue lethality




Genotype
MGI:5296779
hm2
Allelic
Composition
S100a8tm1Hogg/S100a8tm1Hogg
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6J * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
S100a8tm1Hogg mutation (0 available); any S100a8 mutation (10 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• fewer than expected embryos are found at E4.5





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory