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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tfap2dtm1Mos
targeted mutation 1, Markus Moser
MGI:5296818
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tfap2dtm1Mos/Tfap2dtm1Mos Not Specified MGI:5296819


Genotype
MGI:5296819
hm1
Allelic
Composition		 Tfap2dtm1Mos/Tfap2dtm1Mos
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tfap2dtm1Mos mutation (0 available); any Tfap2d mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Tfap2dtm1Mos/Tfap2dtm1Mos mice lack the colliculus inferior

nervous system
nervous system phenotype ( J:177585 )
N
• mice exhibit neuronal responses to sounds in the neocortex
absent inferior colliculus ( J:177585 )
• lost due to apoptosis

cellular
increased apoptosis ( J:177585 )
• at E17.5 in the posterior midbrain leading to the loss of the colliculus inferior




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory